Positive Shift, Social Projection, and Honesty on Social Networking Sites

Positive emotions are prevalent on Social Networking Sites (SNS) because of positive shift—users’ tendency to shift the expression of their emotions in the more positive direction. Emotion expressers aim to gain a more positive impression and elevate their social standing through positive shift, but little is known about the unintended consequences of positive shift for the expressors. Drawing on social projection theory and emotional journey theory, we argue that positive shift can lead to social projection and reduce the expressor’s perceived honesty of other SNS users—an important antecedent of trust and satisfaction with SNS, and this is more likely to occur when the user shifts emotions with higher emotional dissonance (i.e., difference between expressed and experienced emotions). We further propose a diversity reminder as a likely remedy that suppresses the social projection process. Using two experiments, we found evidence supporting these predictions. Our findings provide important implications

The Journey to Self: An Intra-personal Perspective of Emotion Regulation on Social Networking Sites

Although social networking sites (SNS) users often share positive emotions in the content posted online, their satisfaction with SNS and intention to continue using it vary greatly across users. We argue that a key to addressing this puzzle is how content creators up-regulate their emotions on SNS. Building on emotion regulation theory and belongingness theory, we characterize digital emotion regulation in two ways (i.e., positive shift and emotional labor) and propose a dual-pathway model that involves two self-views. By constructing three complementary studies, we find that it is emotional labor, rather than positive shift, that drives a user’s sense of belonging through anticipated self-enhancement (i.e., communal self-view) and felt authenticity (i.e., authentic self-view) and explains the varying outcomes. Our findings reveal the benefits of deep acting and countervailing effects of surface acting. The present research provides important theoretical and practical implications

Ecology of Yuqing County Carbon Sink Calculation and Ecosystem Protection Measures

Based on the remote sensing statistical data of land use of terrestrial ecosystems in Yuqing County, this paper calculates the amount of carbon sinks in the county according to the existing carbon sink carbon density index, compares the amount of different types of carbon sinks, and analyzes their respective carbon sink potential. The results show that the forest carbon sink is the largest, about 2.2 million tons, accounting for 75% of the total carbon sink in the county, showing the great potential of forest vegetation to absorb CO2 through photosynthesis, followed by the carbon sink produced by dry land (cultivated land), about 400,000 tons, accounting for 13% of the total carbon sink in the county; Although the amount of wetland aquatic carbon sink is small, its carbon density is very large, and it has the advantages of short renewal time and fast carbon sink, so it has great potential and can be artificially regulated to increase carbon sink. Based on the above research and analysis, combined with the spirit of the national carbon peak and carbon neutral policy and the natural law of ecosystem development, three measures to protect and increase carbon sinks in terrestrial ecosystems were put forward: (1) continuing to carry out forestry planting and do a good job in forestry protection; (2) stabilizing the surface water area and developing aquatic carbon sinks; (3) Establish a long-term monitoring system to ensure the contribution of carbon sinks, provide support for the protection of ecosystem and the development of carbon sink potential in Yuqing County from two aspects of science and management, and compare the amount of different types of carbon sinks, and analyze their carbon sink potential. On this basis, combined with the spirit of the national carbon peak and carbon neutral policy and the natural law of ecosystem development, three kinds of terrestrial ecosystem carbon sink protection and increase wording were put forward accordingly, which provided support for ecosystem protection and carbon sink potential development in Yuqing County from two aspects of science and management

Molecular insights into functional differences between mcr-3- and mcr-1-mediated colistin resistance

The global emergence of plasmid-mediated colistin resistance genes mcr-1 and mcr-3 has threatened the role of the “last resort” drug colistin in the defense against infections caused by multidrug-resistant Gram-negative bacteria. However, functional differences between these two genes in mediating colistin resistance remains poorly understood. Protein sequence alignment of MCR-3 and MCR-1 was therefore conducted in Clustal Omega to identify sequence divergence. The molecular recognition of lipid A head group phosphatidylethanolamine and MCR-3 enzyme was studied by homology modeling and molecular docking, with the catalytic mechanism of MCR-3 also being explored. Thr277 in MCR-3 was validated as the key amino acid residue responsible for the catalytic reaction using site-directed mutagenesis and was shown to act as a nucleophile. Lipid A modification induced by the MCR-3 and MCR-1 enzymes was confirmed by electrospray ionization time-of-flight mass spectrometry. Far-UV circular dichroism spectra of the MCR-3 and MCR-1 enzymes suggested that MCR-3 was more thermostable than MCR-1, with a melting temperature of 66.19°C compared with 61.14°C for MCR-1. These data provided molecular insight into the functional differences between mcr-3 and mcr-1 in conferring colistin resistance

Plasmid-mediated novel blaNDM-17 gene encoding a Carbapenemase with enhanced activity in a sequence type 48 Escherichia coli strain

Carbapenem-resistant Enterobacteriaceae (CRE) have spread worldwide, leaving very few treatment options available. New Delhi metallo-beta-lactamase (NDM) is the main carbapenemase mediating CRE resistance and is of increasing concern. NDM-positive Enterobacteriaceae of human origin are frequently identified; however, the emergence of NDM, and particularly novel variants, in bacteria of food animal origin has never been reported. Here, we characterize a novel NDM variant (assigned NDM-17) identified in a β-lactam-resistant sequence type 48 (ST48) Escherichia coli strain that was isolated from a chicken in China. Compared to NDM-1, NDM-17 had three amino acid substitutions (V88L, M154L, and E170K) that confer significantly enhanced carbapenemase activity. Compared to NDM-5, NDM-17 had only one amino acid substitution (E170K) and slightly increased isolate resistance to carbapenem, as indicated by increased MIC values. The gene encoding NDM-17 (blaNDM-17) was located on an IncX3 plasmid, which was readily transferrable to recipient E. coli strain J53 by conjugation, suggesting the possibility of the rapid dissemination of blaNDM-17. Enzyme kinetics showed that NDM-17 could hydrolyze all β-lactams tested, except for aztreonam, and had a significantly higher affinity for all β-lactams tested than did NDM-5. The emergence of this novel NDM variant could pose a threat to public health because of its transferability and enhanced carbapenemase activity

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049

A Novel Traction Control without Chassis Velocity for Electric Vehicles

Research on motion control of electric vehicles has progressed considerably, but traction control has not been so sophisticated and practical because the velocity of vehicles and the friction force are immeasurable. This work takes advantage of the features of driving motors to estimate the maximum transmissible torque output in real time based on a purely kinematic relationship, and then proposes an innovative controller to follow the estimated value directly and constrain the torque reference for slip prevention. By comparison with prior control methods, the resulting control design approach is shown to be more effective and robust on an experimental electric vehicle. In addition, a new architecture for a two-dimensional vehicle stability control system is introduced based on the proposed traction control

A Study on the Control Performance of Electronic Differential System for Four-Wheel Drive Electric Vehicles

The electronic differential system (EDS) is an important issue for four-wheel drive electric vehicles. This paper delineates an advanced EDS steering strategy and carries out a careful study of its control performance by numerical simulations that comply with the requirements of ISO4238:2012. The results demonstrate that the EDS feedback gain plays an important role to its control performance, particularly to its steering characteristics. Moreover, the analysis and discussion disclose the mechanism of the relationship between the feedback gain and the steering characteristics, which will contribute to further research and EDS development